I took the IF1 for 2 weeks and then started the IF2. I had a hard time getting the portions right of IF1. First it seemed like it wasn't working and I upped my dosage gradually, then I had like 3 days of nothing but loose stools at least 5 times a day- i believe the technical term is diarrhea. Anyway i had a lot of cramping and pain during that time. IF2 seemed to make it better, but then i got sick with this sinus cold that was going around my office, so I slept for 3 days straight, thus messing up my IF2 cleanse. Tomorrow I am going to start back up, but from what I have heard and read if you are having diarrhea you need to cut back on you IF1. Maybe try just 1 a night. I don't have IBS, but have had digestive "issues" for years, so I can realte to the pain and discomfort. I think doing a cleanse can be pretty tough on your body (although well needed) because you are clearing out stuff that has been impacted for many years. Anyway I hope this helps and feel free to keep in touch via the board. It helps to know what others are experiencing. That's what Laura and I have been trying to do.