Question : Vitamin C & Depression

Any references on Vitamin C's effectiveness on depression?
My brother's been on seroxat for 9 years and recently I started him on ozonated water. He's taking a B complex (lifeplan). He's bought a bike. This may not sound like much but believe me, he's the archetypal couch potato but I can see he's finally coming round to the idea that the problem is pysiological, not psychological.
He knows that he'll have to taper off the medication...I'm just curious as to what effects these drugs must be having on his liver.
I know for a fact that he won't entertain a formal cleansing at this stage. He would certainly be amenable to supplementation. Im presuming vitamin C would help with a liver detox; would it also help with mood elevation?
Any input would be appreciated? Tweet