Cayenne contains a resinous and pungent substance known as capsaicin. This chemical relieves pain and itching by depleting certain neurotransmitters from sensory nerves. In a double blind study, application of a capsaicin cream to the skin relieved both the itching and the skin lesions in people with psoriasis. http://www.althealth.co.uk/services/info/ailments/psoriasis1.php