Just to start to help out here: WHEN did your wife start doing her liver cleansing? I know you said she did 5. (I just did 3 in a space of 6 weeks.) So, perhaps the effort for her is just starting to take effect, and the hormonal confusion is just a side effect of the toxic dumping.
For what it's worth: I know that the bowel and the uterus are very close together, so one will feel the pain of the other: years ago, before I ever heard about colon cleansing, I'd sometimes have a "congested" sort of feeling in the low pelvic area that I thought was uterine. And on the flip side, my menstrual cycle would affect my bowel (bad constipation during period).
I will be interested in hearing from Shelley about this, too!