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𝗪𝗵𝗮𝘁 𝗞𝗶𝗻𝗱 𝗼𝗳 𝗖𝗮𝗻𝗰𝗲𝗿𝘀 𝗰𝗮𝗻 𝗙𝗲𝗻𝗯𝗲𝗻𝗱𝗮𝘇𝗼𝗹𝗲 &#...


𝗪𝗵𝗮𝘁 𝗞𝗶𝗻𝗱 𝗼𝗳 𝗖𝗮𝗻𝗰𝗲𝗿𝘀 𝗰𝗮𝗻 𝗙𝗲𝗻𝗯𝗲𝗻𝗱𝗮𝘇𝗼𝗹𝗲 𝗕𝗲 𝗨𝘀𝗲𝗱 𝗙𝗼𝗿?

Fenbendazole (brand names Panacur C ®, Safe-Guard ®) is a veterinary medication introduced in 1974.

Worldwide, veterinarians commonly use fenbendazole, FBZ, to treat a variety of parasites in animals, such as tapeworms, hookworms, roundworms, lungworms, and whipworms.


Fenbendazole has been known to have a high safety margin for animal use as it is tolerated well, has low side effects, and has a low degree of toxicity.
Following anecdotal fenbendazole cancer success stories, researchers have been experimenting with the “repurposed” use of Fenbendazole for cancer – for animals and humans.

Drug “repurposing” is a new use for a medicine that is different from the original medical indication. Though the Fenbendazole studies are limited, what researchers have found so far is promising for patients with cancer.



Fenbendazole for Pancreatic Cancer


Despite the initial effectiveness of certain chemotherapies, pancreatic tumors frequently develop resistance to these treatments. Moreover, newer methods like immunotherapy have struggled to address this challenging disease effectively. All of which has led researchers to turn their attention to Fenbendazole as a possible treatment. And while there is a great need for further studies, early evidence is showing great promise.

The cancer cells in pancreatic cancer behave in a very specific way when it comes to getting energy and nutrients for their growth. They use special ways to process glucose, amino acids, and lipids, which helps them grow and spread quickly. Scientists believe that the key to using fenbendazole effectively in treating pancreatic cancer lies in figuring out how the drug targets the behavior of these cancer cells.



Fenbendazole for Breast Cancer

One study published in March 2023 investigated Fenbendazole’s ability to treat Breast Cancer while preserving healthy breast cells. This research tested the drug on three cell types: normal, low metastatic cancer, and highly metastatic cancer cells. The findings revealed that Fenbendazole induced significant stress in the highly metastatic cancer cells compared to the others. This suggests Fenbendazole could offer a new, targeted treatment for advanced breast cancer



Fenbendazole for Colorectal Cancer

Colorectal cancer occurs when cells in the colon or rectum grow out of control. Treatment typically involves a combination of surgery, chemotherapy, and radiation therapy. There have been a few very promising studies that looked at how these cells responded to fenbendazole.
Tests showed that fenbendazole not only caused cell death in the cancer cells but also stopped them from growing by blocking a specific stage of their growth cycle.

They also found that the resistant cancer cells behaved differently compared to normal cancer cells. They didn’t respond as much to a natural process called autophagy, but they were more sensitive to another process called ferroptosis, which involves cell death due to iron overload.

This suggests that fenbendazole could be a promising treatment for cancers that are resistant to 5-fluorouracil, a type of chemotherapy medicine that is often used to treat colorectal cancer



Fenbendazole for Lung Cancer

Perhaps the most well-known case of someone treating their cancer with Fenbendazole is a man named Joe Tippens was diagnosed with lung cancer in 2017 and given only a few months to live.

Tippens developed a protocol combining Fenbendazole with CBD oil, curcumin, and Vitamin E which proved successful for his case. He remains cancer-free today and his story has sparked interest in pursuing more in-depth trials of Fenben as a repurposed drug.
 

 
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