Re: Here Comes The Sun

I know there is anecdotal evidence for castor oil and cataracts,
but no scientific evidence that it can improve cataracts exists.
https://www.healthline.com/health/castor-oil-for-cataracts
In retrospect, there is one underlying mechanism which
could explain the anecdotal evidence. Some cataracts
are due to the enzyme "calpain":
https://pubmed.ncbi.nlm.nih.gov/15102361/
and castor oil contains undecylenic acid, which
is an inhibitor of calpain:
https://pubmed.ncbi.nlm.nih.gov/22333440/
Nevertheless, I question whether it is safe to put castor
oil in the eyes, as it is not sterile and could cause
infection.
Also, as for NAC, this is counterproductive, because, in
the presence of metal ions, carnosine abolishes the photobleaching
action of glutathione. NAC does however improve cataracts
if a metal chelator like EDTA is further added, as it was in the eyedrop
"C-KAD" which completed Phase II clinical trials in 2009.
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