Dr. Clark said that "parasites" are the cause of all disease. Well, I bought a Zapper (used it everyday for two months) have done a parasite cleanse, Bowel Cleanse and 4 liver flushes. I can not tell ANY difference in the pain.:>{ That is why I will do a mega-dose of CoQ10. (I was supposed to do it this past week-end, but could not) I have checked GNC and they have 120mg. capsules. SO, I will open 25 to equal 3000mg. and stir it into some honey. I hope this will finally get rid of some of the pain in my knees, ankles, and lower back.( I sound like I'm 70 years old!!, but I'm only 40) I'll post my results when I take the mega-dose of CoQ10.