I began having heart palpitations after I started taking 200 mg. CoQ10 twice a day. It took me several months to realize that was what was causing the palpitations. When I stopped taking COQ10 the palpitations stopped, but also my energy went way down. Now I am taking 200 mg. once every two days, and it still increases the frequency of palpitations, but not to an excessive degree. I think it would be better to find a 100 mg. dose that I could take once a day, or possibly even less. I am 160 lb female.