i personally take Lugols on an empty stomach and have no problems with it at all. I guess it depends on ur stomach sensitivity.
I also dont react at all to high dosages of Vitamin c.
I take 100mg Lugols each morning with a big glass of water . And i do that since 1 year. No problems.
I took it with vitamin c once and it gave me vertigo like crazy. (maybe been a coincidence..... who knnows) but since then i never did it that way again.
Some say body converts Iodide into iodine. And food turning Iodine into iodide. I guess everyone has his own theory here. And in the end it all depends on ur body. Either it converts stuff into stuff that it needs or not.
Since i cant tell what my body does i rather have Iodine and Iodide as lugols.