What you describe as affecting your hands could be psoriasis. Psoriasis is an autoimmune condition which causes red itchy bumps (blisters?). Psoriasis and most all autoimmune conditions are caused by dysbiosis in the gut. The fact that you got these "blisters" after taking Bactrim suggests that you may have a intestinal candida overgrowth. I suggest that you do a google search for images of psoriasis. See if Psoriasis looks like what you have. I had a patch of psoriasis on my big toe and when I treated my candida, it went away. Good luck.