Dr. Jarvis always recommended taking Iodine with a couple teaspoons of ACV to promote absorption... and even then to sip it throughout a meal...
Ive done that.. Ive taken it without ACV.. during eating.. on an empty stomach, etc.. all different ways..
I never noticed anything particular with the ACV.. Though sometimes it seems when I take a LOW dosage (1 drop Lugols 5%) on an empty stomach at nighttime it seems to have a greater effect on me than a higher dose.