I have alot of problems with kidney stones and my kidneys have been hurting. never had problems with my lab work but a month after starting the DE I had more lab work and my Dr. said my eGRF lab was at 40, and its not supposed to be below 60. my creatinine was 1.4....kidneys not filtering properly...stage 3 CKD. could possibly be the DE. or just progressive disease the DE aggravated for now. The DE definitely chopped a bunch up though and I had more energy with it. I know there are supposed to be alot of health benefits. You can treat your pets for parasites too according to weight. wolf creek tri pod website or something like that gives the details and more info on it. Just drink lots and lots of fluids!!!