As far as my own "gut" tells me - the rage and anger come from PMS. It's been consistent most of my menstruating years.
Plus, I'm going through a divorce and my daughter is going through issues too, and so I have *a lot* going on. (So some of the emotion is normal).
But what I did notice is that over the summer, I felt very down. Very "in a funk" like my mood was super low and that is really unlike me. And I think *that* was Lyme's related - it was ever since I got it (and I know the day I got it b/c I think it was from a spider bite and I felt the bite).