Re: Young woman's ovaries destroyed by Gardasil: Merck 'forgot to research' effects of vaccine on female reproduction

First of all, this is isn't really "newly published", it's from last year:

BMJ Case Reports 2012; doi:10.1136/bcr-2012-006879

Once again, this "study" has all the hallmarks of the anti-vax movement's continued struggle to find some kind (ANY KIND) of scientific credibility by trotting out biased (COI: one of the authors is on the board of an organization that opposes Gardasil)
and shoddy "research".

A single case in a single study is NEVER the definitive word and - mark my words - a large scale replication study, if ever undertaken, will NEVER validate this study. The obviously biased and highly speculative conclusions have no real body of supporting evidence, it’s all laughable conjecture, the BMJ should be ashamed of accepting this trash for publication. If A, B, C, D are not the cause… Then it must be W? This was a fishing expedition for carp at the top of Mt. Everest! There are many other letters in the alphabet between D and W! There is no evaluation of the scientific plausibility of a mechanism to retard ovarian function. To associate Gardasil specifically and uniquely with ovarian failure requires a fundamental misunderstanding of what a vaccine is, what it does, and how it works.

And - With nearly 60 million doses of Gardasil administered worldwide to date... Wouldn't someone have noticed this by now? Where's the epidemic of teenage menopause? Are they ALL on oral contraceptives and have masked symptoms?

There was a large scale evaluation done in 2011 from the data collected from electronic medical records by the Vaccine Safety Datalink (VSD) program. The VSD monitors almost 9 million patients in a number of large managed care organizations around the United States, nearly 3% of the U.S. population is monitored.

In 2011, VSD reported:

"... active surveillance (called Rapid Cycle Analysis) looked at specific adverse events following more than 600,000 doses of Gardasil, such as Guillain–Barré Syndrome (GBS), stroke, VTE, appendicitis, seizures, syncope, allergic reactions, and anaphylaxis. No statistically significant increased risk for any of these adverse events was detected after vaccination."

In terms of quality and validity, VSD evidence collection, analysis and astute conclusions rises magnitudes above passive collection modalities like VAERS and single case studies such as this one. Any conclusions gleaned from VAERS are total conjecture and no statistical analysis is required or even attempted to establish irrefutable correlations with post vaccination adverse effects as reported to VAERS.
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