Iv been reading heaps of forums many derms give there patients imuran for chronic exzma, contact dermatitis and auto-immune skin conditions I even read mums that have there 11 year old daughters on it for a couple of yearssome have been on it for years and have been in 95% remission and have there lives back on track! It's a no brainer for me I will definately be trying this soon.. I guess our condition is to chronic for most treatments time to bring out the big guns!