However, a rat study lasting for 3 generations found no reproductive toxicity or effect on the parents or offspring at 30 mg boron/kg/day. This dose corresponds to 17 grams of borax for 60 kg ingested for 3 generations! In another 3-generation study no problem was found at 17.5 mg boron/kg/day, corresponding to 9 grams of borax/60 kg, while the next higher tested dose of 58.5 mg/kg/day, corresponding to 30 grams of borax/60 kg, resulted in infertility. Therefore we can assume that the safe reproductive dose is up to about 20 grams/60 kg/day.