Re: Egaten + Ivermectin

Honestly, I completely distraught at hearing this. Were you able to get the fasinex in s.a. or did you order the trivantel? Did you take it with a fatty meal? How many doses have you taken already? Did you see any flukes in your stool when you took it?

My experience with taking the egaten was that it worked. It wasn't the veterinarian form it was the egaten. I took 10mg/kg. I only had one dose, I could only get one dose. It worked within the first 5 mintues. I took it with lots of bacon, ham and eggs. My bile duct was already ruptured and blocked from me pushing on a fluke during a coffee enema two days prior. So, the flukes didn't clear. After 5 days of the dislodged masses circulating within my abdominal cavity thru the tracts they burrowed they came back to life. Now they are resistant to it.

Some of the veterinarian studies use ketoconazole and methimazole to inhibit the metabolism and detoxification of the triclabendazole in thier studies. I couldn't stomach the methimazole very well. The ketoconazole I could handle better. Technically, the methimazole is an antithyroid drug and the ketoconazole is a antifungal. The ketoconazole also blocks the absorption of testosterone and was once considered to possibly be a male contraceptive. The studies I read didn't show any long term effects and once the medicine was discontinued then testosterone levels returned back to normal. From what I remember about grapefruit juice, I believe it was 70% effective at inhibiting the cyp3a4 enzyme. One of the main enzymes used in the p450 pathway to detoxify drugs. It's the enzyme ketoconazole was used to target. Bromelain also targeted another one so I took that along with the grapefruit juice.

Honestly, I think both the ketoconazole and methimazole is just too hard on a person's system to take. The grapefruit and bromelain are simply juices that don't have the side effects. But, they don't work as well either. Maybe the grapefruit juice should be added during the first dose of the triclabendazole. It's tough to say. No one mentions it, but maybe it should be.

I know there can be complications from having a fasciola infection. They are extremely mobile. It was assymptomatic for me for the first 8 months. Are you sleeping at all? Did you see any flukes in your stool once you took the triclabendazole?