It is hereditary...she wasnt full blooded...it comes from Europe, Scandinavia, Irish, Scottish, etc...I have it in both hands and both feet. Had surgery, needle procedure, Xiaflex, and tried everything natural. DSMO didnt work for me. Since I have multiple sites, I can try one location at a time. DSMO causes an increase in the size of my cord. Vitamin E along with DMSO was like fertilizer, caused quick problems and cord growth. Vitamin E alone did the same thing, but slower growth. Nothing natural has worked at all and most of the time increased my bad symptoms. The most success I was with Xiaflex, but it took many injections that are $3000 a pop, and I think there are some side effects I still fell today, one year later. But it did make the DC cord fully break in one finger and it hasnt returned, where all other treatment including surgery only offered temporary relief.