I agree. I think the majority of candida likes to hang out in the colon. Just like the majority of our friendly flora resides in the colon. For those that deal with candida just past the duodenum(myself) Lufenuron is designed to be absorbed into the fatty tissues of the small intestine...probably not much of it reaches the colon although. Lufenuron might not be effective for those that are "not" dealing with "fungal" candida. Maybe thats why lufenuron did not work for you is because more of your candida resided in the colon.
Glad the enemas are working for you. Whats interesting is that Bee Wilder used to do nystatin enemas and said in the past they helped her. But currently she doesnt want to contribute her healing process to them.
The way I gauge of where the candida resides the most is how bad my reaction is to no-no foods and how long those reactions are after I eat. For example, I can react to a no-no meal 3 hrs after I eat ( just past the duodenum area?) and then again 10-14 hrs after I eat (colon area). My symptoms seem to be worst once the no-no food reaches the colon area which would back your idea that more candida resides in the colon. Thats when the enemas can be effective.