My Dr called today to tell me that my estrogen level was high...398. She wants me to get an ultrasound to find out why. Has anyone else had this? What caused it in you? I am 50 years old and my periods have been irregular since January, about 45 days in between. I thought I was just starting menoupause but I guess not. Apperently high estrogen causes the smae symptoms. Hot flashes, irritability, adn so on...Thanks for your help.