Re:

So, a mere 100 mg a day (about 1/18th of the AMA amount) is probably not an issue for most mammals weighing over 100 pounds, would be my expectation.

But, consult with your physician before doing anything. Remember, FDA rules do not permit the statement "prune juice cures constipation" to be put on the label of prune juice until studies are conducted - for a very good reason. Tweet