My hands on experience is 2-fold... for me it an anti-spasmatic or a relaxant it just relaxes me, though I have given it to someone on an empty stomach and probably a little too much for their body size and they experienced the emetic side of lobelia. Schulze and Christopher call lobelia a thinking herb that accelerates other herbs in doing their job.
Having been around here a while I know you know that no herb is to be used on its own as a "medicine" rather a whole lifestyle of health must be created and herbs assist us in that.
For me all disorders start with juicing. 30 days minimum and a colon cleanse.