Unbound High Copper & Cortisol

Hey all,

Anyone know how unbound copper affects cortisol?

Does high unbound copper cause high cortisol, or does high cortisol cause high unbound copper?

What is the adrenal-liver cascade that causes ceruloplasmin to be produced? Do the adrenals detect copper in the bloodstream, or the liver?

How do the adrenal and liver share dialogue on copper?

Copper in the body is one hell of a paradoxical subject.

I was poisoned by copper particles while my adrenals were already dysregulated, so it seems like this is just a crazy, unstoppable, paradoxical scenario.

With the ambiguous information and bad experiences I've had so far, I just don't know where the hell I'm going with this anymore - it's insane, to put it mildly.

Nobody seems to know about the exact mechanisms in the body, which is frustrating.

Any ideas or abstract thinking on the subject would be great, thanks.

Best,
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