Re: Vitamin E Enema - Colitis - Overdose/Toxicity?
I was just thinking of this!
Vitamin E becomes a PRO-OXIDANT and acts similarly to oxygen reactive species when vitamin C levels in the body aren't kept at the right ratio in accordance to levels of vitamin E. Also, Coenzyme Q10 keeps vitamin E in check by donating electrons so that it becomes inert when it reduces free radicals. So going above the RUL would surely just increase free radical/pro oxidative damage if vitamin C levels and CoQ10 aren't supplemented as well!
Saying this, it does seem to help some people by taking it in an enema with ulcerative colitis. So you have to weigh up the benefits with the cons like with all things. If it is going to stop your bleeding, and possibly save you from becoming anemic or having your colon removed, then the temporary oxidative stress is probably worth it.
To be honest though, I'm not entirely sure, but I would think if blood plasma levels of vitamin E above the safe upper limit were reached, the anti-oxidant capacity of the vitamin will be reduced unless vitamin C and COQ10 levels also went up.
I'm currently experiencing a colitis flare up and losing a lot of blood, so I'm hoping this vitamin E thing is going to buy me some time!