One of the biggest differences is that progesterone dominance kills the sex drive while estrogen enhances it.
LOL!!! well that's me ZILCH sex drive! and apparently i have uterus atrophy also. No acne, only mood is sometimes i feel like crying for no reason but i have low thyroid function along with incredible fatigue. and when i was on progesterone cream therapy my ZILCH sex drive went further north, if that is possible! I was on Vitex for months and developed abdominal bloating, swollen soar breats and my uterus felt swollen also. I got told to persist as bodily hormones were balancing out - apparently progesterone turns on estrogen receptors which is meant to explain the bloating. Zilch zilch zilch!