I've tried this supplement. It's given to people when they overdose on acetaminophen. I've read it's also supposed to be good for the liver. I think it's high in choline so if you think you have tmau then maybe it would be better not to take it. If you try it, just make sure you get just NAC with nothing added to it, cause the 2nd bottle of this stuff I got had selenium and molybdenum added to the NAC and for some reason it just made me feel sick whenever I took it. I think NAC by itself shouldn't have any negative effects, even in really large amounts because people who overdose on tylenol are given a lot of it. Just be careful if you buy this supplement if anything else is added to it like selenium cause that can't be taken in large amounts.