Somewhere on the internet is some Chronic-Fatigue-Syndrome dr's recipe for makeing Mutaflor (can't remember the name, but try a search on lymenet.org). I think Threelac may be a better value than Symbion and some believe those bacteria crowd out other beneficial bacteria although they are useful to crowd out yeast and fugus during the acute stages. Treating leaky gut concurently is also helpful as is making sure the lymph in the gut area stay clear by ensuring proper elimination.