Re: This Metametrix test proves you should not rotate the antifungals.

That is something that also happen when you don't complete the treatment. If you take Fluconazole for 15 or 20 days, that is not enough to eradicate a fungal infection because Fluconazole is "fungistatic" and you will need a long term treatment to get fungicidal action from it. But if you Dr. doesn't have any idea, he will prescribe you only one month because his appreciation, then those strains of yeast that survived (the strongest ones) will multiply. When some time pass, you will have the infection back with an stronger fungal strain against fluconazole. Vaginal yeast treated with 1 tablet is the same. Later on, when you come back with Fluconazole, the drug won't do anything to that new stronger yeast family. I don't know how long you have to be on a systemic drug to eradicate an fungal infection completely. According to the limited information, it should be for months with a proper effective antifungal. Don't make the worst mistake I have made of stopping the treatment. If the yeast isn't killed at all, when it comes back will be stronger than before and every time you fail, stronger it will be.