Chitinase ::: part II

I started a thread on the use of chitinase a few posts ago and starting a new thread so this information does not get buried. For those who have not read the original post, chitinase is an enzyme that is found naturally in some foods such as papaya seeds, barley seeds, avocados etc. Chitinase works by eroding the protein coats of parasites, yeast etc which allows the immune system to effectively attack.

Anyhow I am still researching this and ran across this medical journal article that appeared in PubMed which is the complete database of medical journal articles that the US based National Institutes of Health provides. So it is a very legit source of information :)

http://www.ncbi.nlm.nih.gov/pubmed/17472487


Effectiveness of dried Carica papaya seeds against human intestinal parasitosis: a pilot study.

Okeniyi JA, Ogunlesi TA, Oyelami OA, Adeyemi LA.
Department of Paediatrics and Child Health, College of Health Sciences, Obafemi Awolowo University, Ile-Ife, Ilesa, Nigeria. akinyemiokes2@yahoo.com

Abstract

The tropical fruit Carica papaya and its seeds have proven antihelminthic and anti-amoebic activities. To determine the effectiveness of air-dried C. papaya seeds on human intestinal parasitosis, 60 asymptomatic Nigerian children with stool microscopic evidence of intestinal parasites received immediate doses (20 mL) of either an elixir composed with air-dried C. papaya seeds and honey (CPH) or honey alone (placebo) in two randomized treatment groups. Repeat stool microscopic examinations were conducted 7 days postintervention for intestinal parasites. Significantly more subjects given CPH elixir than those given honey had their stools cleared of parasites [23 of 30 (76.7%) vs. five of 30 (16.7%); z = 4.40, P = .0000109]. There were no harmful effects. The stool clearance rate for the various types of parasites encountered was between 71.4% and 100% following CPH elixir treatment compared with 0-15.4% with honey. Thus, air-dried C. papaya seeds are efficacious in treating human intestinal parasites and without significant side effects. Their consumption offers a cheap, natural, harmless, readily available monotherapy and preventive strategy against intestinal parasitosis, especially in tropical communities. Further and large-scale intervention studies to compare C. papaya with standard antiparasitic preparation are desirous.
PMID: 17472487 [PubMed - indexed for MEDLINE] Tweet