When you say you can't handle the probiotic, what do you mean? I had really bad leaky gut and couldn't eat anything without an allergic reaction. I think if you are at this point then your immune system is going to be in pretty bad shape. I would start with a probiotic, you're probably going to have a herx reaction to it but you just have to get through it. Threelac helped my leaky gut to start with, after that it didn't seem to do much. But once I had my immune system in better shape, I could start on anti-fungals & anti-biotics with probiotics. I'm around 6 months into treatment now, and about 80% to full health overall, but that's with having die off every day. I couldn't have held a job whilst going through it.