I've been doing the coffee enemas daily for cancer. This web site http://www.cleanse.net/newsite/articles/coffee_enema.html, says "It is interesting to note that drinking a cup of coffee has an entirely different effect from that of using it as a cleansing enema. Drinking coffee causes the following problems: increases reflex response; lowers blood pressure; increases heart rate; causes insomnia and heart palpitation; over stimulates the adrenals; irritates the stomach; and leaves a toxic residue in the body. A coffee enema, when done properly, will not produce these effects."