Drug metabolites and urine Therapy - is it a problem?

Addicts, and the "chemically dependant", will no doubt have metabolites of the drugs they take in their urine.

Anyone have any info on how this affects Urine therapy?

Or how re-ingesting these metabolites, by drinking their urine, will affect them, their drugs?
Will it make you high, or enhance the next dose at all? This could be serious if it leads to overdose, so I think someone would know about these questions.

What time of day would have the least drug-metabolites? for eg., Morning, if you don't take any doses of the drugs after 5 pm? - is this better for Urine therapy, to get less of the drug metabolites?

questions questions, I am allways asking questions...
Karlin