I just go buy the directions that's on the bottle of dandelion. Mine says once or twice daily. It was helping at first but now the edema wont go away. I have a Dr's appt on the 19th. I'm going to try to get my doc to prescribe Armour thyroid. I wont touch the Synthetic stuff. Half of my hair is gone. I have all the classic symptoms for low thyroid. I'm 51. I looked up fluid retention/edema and I read that it could be low albumen. This is from the liver. Iv'e been having alot of pain/discomfort in the liver and kidneys. A sign of low albumin. I read that it can cause whole body edema as in my case too. Of course it could be something else too. Whats wierd is they say to eat Watermelon which is a diuretic, but when i eat it, I swell even more. Somethings off in my system. Hopefully the doc can find out what it is in the blood test. I hope this helps.