I think everyone has at least microscopic blood parasites etc in this day and age, and I REALLY don't think these herbs could do anything but help, they are also a gentle colon cleanse at the same time.
If you DO have parasites however, you will have a few bad days before it gets better as die-off from toixins etc can be draining, but like others have said, once you get through that, WOW.
A little pain 1%, (not for me though because I was already so bad before that it was no difference for me) and 100% GAIN. :)