Becaused you asked, I do not see any benifit in takeing it this way and you will not see me doing doing it. If I was trying to get it in my brain more than thru the blood vessels, I would add DMSO. But it is such a small molocule (not much bigger than a water molocule) that I really don't see any need for that either. My educated guess is that it diffuses right thru it with out any problem.