I haven't done it yet, I did go to twice a day, but I have the 12 drop ceiling and have not been able to get thru it. Even taking 10 drops on Wednesday I herx'ed to much (runny stools). I had been up to 14 drops but then realized there was Natural Vit C in the grape juice, so I stopped the juice.
In the past day or two I thought that I should try and split the dose or 2 , 3 , or 4 times a day. I haven't done it yet.. but Jim Humble talkes about doing it in his book. I've also thought about doing it IV, and I know how and have the credentials. When I mentioned it to my wife, what a weird look..lol. I told her I would not do it but If I had cancer, that is how I would do it I think.