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Fecal Body Odor Causes and Possible Cure
 
qazmop Views: 14,623
Published: 15 years ago
 

Fecal Body Odor Causes and Possible Cure


I've had fbo for 5 years now and I've tried everything. Colon cleanse, long periods of strict diet, exercise, weightloss, probiotics, chlorophyl, laxatives etc and nothing has worked(many people also report the same). I've come to the realization that this problem comes from leaky gut or having a permeable colon wall.
Simply stated, fecal matter is being absorbed into the blood stream. This is the reason why we have that "aura" of fecal scent(the smell eminating from the pores). I've read posts of people doing colonoscopies and not finding any problems or people using cleansers and getting colon hydrotherapy with no results. I see people who are obese and don't have this problem. I can eat healthy for months and still get fbo and I'm in great shape. Some people have chronic constipation/diarrhea yet still don't have fbo. How else can we have a fecal odor if people have the same symptoms as we do yet don't have fbo and how come colonoscopies show no problems?

Read what Dr Stoll wrote on his site:
"If you have Leaky Gut Syndrome , your colon will leak fecal material back into your bloodstream and you will have a fecal odor in your breath and on your skin. There are only 4 ways the body has to excrete toxins: dead skin (including sweat), urine, stool and breath. If colon stuff gets back into your blood, those other sites will have that odor."

Here's what I've discovered:
There's a toxin called "Zonula occludens toxin" which is produced by the "Vibrio cholerae" pathogen which increases cell wall permeability (ability for matter/molecules to leak through colon wall).
Sources:
http://en.wikipedia.org/wiki/Zonulin


http://www.jbc.org/cgi/content/abstract/276/22/19160

It has implications with coeliac's disease and type 1 diabetes
This study found that Zonulin upregualtion is associated with people who have type 1 diabetes and their relatives (my mom has type 1 diabetes):

http://diabetes.diabetesjournals.org/cgi/c.../full/55/5/1443


The good news:
ALBA Therapeutics is developing a zonulin receptor antagonist, AT-1001, that is currently in phase 2 clinical trials.
(source: wikipedia)

From Alba therapeutics website:
"It is known that altered intestinal permeability (ďleaky gutĒ) is a hallmark of CD and tracks the severity of the disease. It is likely that leaky gut is both a cause and a consequence of the disease, facilitating transport of gluten which then triggers an inflammatory process, resulting in tight junction dysfunction ("leak") which can be blocked by tight junction modulators including Alba's lead product candidate, AT-1001."

http://www.albatherapeutics.com/ProductDev...80/Default.aspx
 

 
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