In the mist of battle, The Killing Zone - and its effects
Building a formula requires one take into account another factor - Time.
Half-life for a med is different for each med.
Since different antiparasitics work on different stages or processes, and the half-life in you is different than the half-life in the parasite, meds that have some kind of conflict can be worked around. The most common technique is stagger the dose times.
I have found this "Conflict" to be mostly a rubbish argument though, it is not what happens in the human, but what happens to the
parasite that matters.
Some meds require food, like DEC.
All meds except a few, should be taken with a buffer like Yogurt, or Milk product, to prevent full strength contact with the GI lining. Over time this becomes important.
Levamisole and Pyrantel are important AChE antagonists. I have come to experience the effect with complicated, systemic, Red worm infections like Strongyles. Controlling out of control infections sometimes take drastic measures, until better formulations are found.
Brute force AChE slows, then stops a few species that don't respond to any Zole. Al, Ben, Fen.
So dosing Pyrantel in the upper levels, with Levamisole in the upper levels, can provide a means to arrest some out of control infections.
Not an ideal trick. But Pyrantel puts worms to sleep. Levamisole can Arrest muscle movement in some species, and accelerate movement in other red species.
So putting worms to sleep first, then dosing Levamisole second, like an hour later, goes smoothly in these rare situations.
More ideal is a lower dose of Levamisole (say at or below 1.25mg/kg/D). Other meds and supplements can be used to accomplish this.
There are many other situations, where the meds may meet (taken during the course of a day), like if one is doing a periodic ~ GI maintenance formula, or GI clearance schedule using Pyrantel, like for a complicated
Ascaris formula, or fighting multiple hyper parasitic infections at one, and/or if one is using Levamisole as an amplification factor.
Amplification factor meds are Albendazole, Levamisole, and combination meds that target multiple aspects of an infection at the same time.
So, for general and universal ampflication of a meds strength, one can combine low dose Albendazole (2X boost) at 8mg/kg/D plus Levamisole (5X boost) at 2.5mg/kg/D, to either FenBen, OXBen, or OXFen or many other meds. Depends on what you are fighting.
OXBen/OXFen has some 10X the strength of their non-ionic core meds, when the species is in the target hairs of these meds.
Simply put into a formula, one can achieve the desired killing strength, using lower dose levels of all the meds.
For Example:
Albendazole of 4mg/kg/D, or 4 doses/D of 1mg/kg is the threshold of use as an amplification factor. It is a gateway into human tissue.
Levamisole at 4 doses of 0.32 mg/kg is a threshold level as an amplification factor, it affects your immune MUC receptors.
(2.5 mg/kg doses of say OXBen) or (2.5mg/kg doses of OXFen), now are more powerful by these cofactors of ALB and LEV.
As an estimate
Say 1.5X Albendazole strength
Say 2.5X from Levamisole strength
Say 2X OXFen over FenBen strength
So The formula of 3 meds is 7.5 times stronger in this tuned formula, than 5mg/kg/D FenBen dosing alone.
The risk in this, is that very precise measurement of Levamisole and OX meds must be made.
If one takes too much Levamisole or OXified antiparasitic in combination, the killing strength can be too high during early die off situations.
Later on, the correct dose and mix of a formula can be ascertained by experience, not by jumping into the middle of an infection.
Slow ramps into the killing zone is a safer method.
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Invermectin and Moxidectin are not neurotoxic, just the die-off toxins.
Moxi in particular should be dosed using 40 - 80 ucg/D doses, so not to ramp too quickly. Dose these small dot doses over a period of days will provide a gentler way to increase the 20 day half-life of this med. Ideal killing occurs at some 600 - 800ucg/kg, which takes a few weeks to enter, using this small dose method.
As for Doxycycline, Ivermectin and Levamisole having some effect on the intestinal "dragons", Let's Say Doxy is antagonistic towards certain DNA strand weaknesses, as well as being an antibiotic. Invermectin has various effects on both female worms, and Red worm Eggs. Levamisole is both an Immune system alteration to Mucin, and a strength Amplifier of other meds.
I do not "see" this formula, and have no idea why it is helping you.
I can say that Doxy, IVM, LEV are all primarily RED meds, in my view.
FenBen, or OXFen may also play into your situation. Pine Needle oil caps may also play into your infection, if there is a RED
parasite DNA inside your parasite. If not, then your infection could be affected by red meds, because you have a RED worm co-infection.
From the discussion of stages, I would be concerned that sufficient minerals, metals, and nitrogen catalyst are taken. L Carnitine, B3, and sulfur, sulfates, help maintain humans in the presence of high nitrogen environments. Selenium is essential too. Magnesium Sulfate, Potassium citrate may be required to prevent exhaustion of essential stores. B50 is very useful during a fight.
Symbiotic infections often occur. The inside of a nest or adult is a perfect nitrogen environment, where other stages, or species can live.
Damage by high energy worms may need to be addressed by your formula. Pyrantel lowers energy of reds. Thyme leaf lowers energy level of REDS. Oregano oil with some Castor oil in and around eyes, ears, nose throat, can help keep worms from these areas.
Papain helps digest proteins of
parasite nasal birth. Bentain, Bromelain, I have also read lumbrokinase may also aid.
CQ10 400 or higher speeds healing to damaged tissues.
OXFen is generally a red med, but certain worm like small Strongyles respond to OXBen, sorry I cannot shed light on this, that is why challenge test data is so essential beforehand. It may also be possible for a species to have stages with different weak points. Detailed challenge results for all the primary meds, and DEC, Prazi are required to prevent such firefights. Don't get burned early.
I think you may have rushed into treatment without a fully configured or balance approach, and now you are in a firefight. A safer route is to have a mineral, metal, support amino tuning, and herbal routines up and running prior to running head long into a Kill.
Preparation is key to getting to the other side, and into a remission from a hyper infection.
This "all - or nothing" approach has risks.
I would slow the movement down to a crawl, Grams of Thymus Vulgaris/D?, or Pyrantel? to lower the amount of damage being done.
Without a road map of what challenge meds you reacted to, it is difficult to assess risk.
Remember, a med may work on a single species, at a nominal dose, but affect several others at a maximum dose level, making the fight much more complex.
Meds at higher levels become risky, if there are unknown co-infections you can stumble across.
A slow methodical plan to clear the known or suspected infections, carries less risk, and is more sustainable, than an all or nothing approach.
Observe, take notes, and work the, or a problem, at one time.
Multiple problems can easily get out of hand, requiring intervention, a not so nice situation.
Have ALA, CQ10, L Carnitine on hand, along with a list of Alkaline and other emergency meds, to throw a blanket on any run away infection.
Have magnesium citrate, potassium citrate, MSM, Distilled water, and such, in such a situation.
Maybe you get lucky with a species that is easily wiped out, maybe you don't get lucky.
Hope for the first, prepare for the latter.