On Blasto and gastro enteritis 
shroom
10 y
1,986
Hi Folks.
The last post I did I was going on about a new bacteria I found in the gut, suspecting chlamydia.
I am happy to say, it was some other bug...not sure which.
Last week I contracted a serious virus, and it took me down for 30 hours straight. It was the sort of "stomach virus" one can catch from cruise ships etc; a rotavirus or norovirus something in the Caliciviridae family anyway.
I could not do stool exam during the course of the illness because I was not functional. However, I was able to do direct observations soon after.
The observations are important, because it gave clue to the events in the bowel's biochemistry while fighting something serious.
The stool contained very large amounts of crystals (splinter type), which indicate there is an attempt by the body to produce an initial chemical response to flush, and alter PH. This I assume is stage 1. The second stage is antibody infusion, which is what I saw today.
So...let me back-up a bit.
As some know, I have a primary cystic parasite of the plasmodium spp. and unknown.
Many months ago I picked-up a co-infection from another parasite, likely related to blastocystis. This one created symptoms of IBS and gas.
When I took my first stool exam shortly after the virial illness, I saw thousands of angry "blasto-type" parasites in a state of heavy reproduction. But, my symptoms from this bug was declining.
Today I was able to observe the parasites in a state of degradation from antibodies!
I am hopeful, and if correct, the illness may have serendipitously generated antibodies for this strain, while in the course of fighting the virus!
It is a very adaptive bug, but it only has so many mutations per host.
Unfortunately the primary parasite is not so inclined to be affected, because of the protective cell membrane of the cysts.
So I started thinking about this, and it occurred to me, that the methods of "stool transplantation" could hypothetically cause antibodies from one host to fight the parasites of another. In fact multiple donors could increase the chance of assisting the host recognize and amplify a proper immune response to any number of parasites. Just a thought.....
Shroom
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- Re: On Blasto and gastro enteritis FL 1953
10 y
1,502
This is a reply to # 2,168,629Getting someone's antibodies could help you fight what you have, but it would not cause your body to make more T cells. T cell suppression is one way parasites have adapted to survive in their host. For plasmodiums, many down regulate the Interleukin 2 Receptor, Alpha (IL2RA) gene. Combine this with partial methylation pathway obstruction that allows more metal accumulation and they have found a way to survive our immunological onslaught.
- Re: On Blasto and gastro enteritis shroom
10 y
1,637
This is a reply to # 2,168,692Advertisement
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Good point, but good thing we have built -in redundancy systems that can override these obstructions given the right amplification primers or circumstances.
Glutathione production is a good example, but this is a rare event in terms of autocrine reaction on a scale large enough to detoxify or self-cure a disease--it does happen though.
If foreign antibodies can act like a sort of complimentary "hapten", it may be possible to evoke a TH1 cascade large enough to trigger lymphocyte activity (a guess), which could ultimately lead to pathogen recognition.
I doubt however, it would work effectively on certain protozoan infiltrations.
Never-the-less these are are just hypothetical scenarios which could also have serious immunopathologies involved....so don't try this at home folks!
I think and still am convinced, that the best way to beat these parasites is to damage any cystic stages they possess, and they all have this in common.
It should be noted as well, host immunity and defects in these systems are often the result of becoming infected in the first place.
Shroom
- Re: On Blasto and gastro enteritis FL 1953
10 y
1,600
This is a reply to # 2,168,909I agree about the cystic stages. I can kill my pathogens, I just kill them all. The reason I can't kill them all is that my immune system does not have access to them. This is because of cysts, biofilms, or they are in areas sequestered from immune response.
- Re: On Blasto and gastro enteritis shroom
10 y
1,762
This is a reply to # 2,168,956Yes exactly--like the prostate for example. If there was a way to trigger an awakening of "all" cells to the signature molecules of the invader, it might cause a built-in response that could see the complete elimination of the target.
This is possible, but dangerous. The same phenomenon could eliminate cancer cells...like a default button.
It's like the body has "sleeper" capability that is only activated by very specific stimuli, like some kind of archaic code.
The problem with this is, once it it turned on, it could have unpredictable results.
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- Re: On Blasto and gastro enteritis shroom
10 y
1,762
- Re: On Blasto and gastro enteritis FL 1953
10 y
1,600
- Re: On Blasto and gastro enteritis shroom
10 y
1,637
- Re: On Blasto and gastro enteritis FL 1953
10 y
1,502
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