Ah, thanks for relating your experience.

What about other forms of B12?

(Air hunger was one of the scarier symptoms I used to get frequently.)

What about sodium? Do you add salt to your diet?

Laredo, just curious about how one tests for histamine. Please reply. Thanks.

@Laredo

I've been reading a number of your posts and we have some strong similarities, even though our root causes may be different. The Histamine info is bang on, I've noticed this for sometime (due to an infection with Blastocystis I have) and have always felt better on supplements that lower Histamine (ex. Vitamin C, Methionine, TMG, Magnesium, and Diamine Oxidase).

I agree to stay away from the Vitamin B12 and Folate (in any supplemental form) if you feel you have High Histamine. Both can cause a huge rise in Histamine and cortisol is your first defense for lowering Histamine. It's no wonder Cortisol is constantly pumping out, and therefor draining your adrenals.

Otherwise, keeping to a Low Histamine Diet as much as possible. If you do want to have some Histamine containing foods, I would look into Diamine Oxidase (one of the enzymes that breaks down Histamine) to take BEFORE you eat high histamine foods.

After dealing with that finding the cause of your raised histamine (gut issues, copper issues, ....etc...) is naturally another important step)

**NOTE - This is NOT to say this is the cause of all Adrenal Fatigue - only that Histamine and/or Unavailable Copper really is messing some of us up**

The reason your histamine levels increased was not due to the methylcobalamin, but because you were using FOLIC ACID -- which will raise histamine because it blocks the natural forms of folate -- folinic and methylfolate -- which help to break down histamine.

You probably got the advice to use folic acid from Carl Pfeiffer? His research is 20 years old, if not older, before we learned the importance of natural forms of folate.

Laredo, many of your symptoms match mine (I hate the hunger feeling!) but I don't get low blood Sugar though many of it's symptoms match mine, I don't sweat or tremble. Instead, I suffer from HIGH blood Sugar and feel really lethargic and get a vertex headache when my insulin spikes up after eating sugary stuff.

I didn't know this until a few months ago and have stopped eating sugars almost entirely after finding out.

Erratic blood Sugar can be due to liver congestion, high blood sugar can be due to high cortisol also. As discussed in the past, Seriphos didn't do anything for me so I'm concentrating on my liver now and hope my health improves. The insomnia is my #1 problem. Unrefreshing and disturbed sleep. Hopefully lowering histamine and making copper bioavailable again will help with that.

I've been on 200mcg chromium polynicotinate 2x a day for nearly 3 weeks and it hasn't controlled my blood sugar spikes at all.

Undermethylating sucks :(