parazapper
I agree with most of what you are saying except for the scare tactic:
>- and not need liver help or die should go on doing it
Interesting that in that 10 year study of almost 8000 participants, only 3 needed to be removed due to liver difficulties. That is a very low percentage. Compare that to statin drugs or blood pressure regulators. From what I have read, the damage rate from nicotinamide is higher than that for the niacin. If you have data that dispels that, please post it. I would also like to interject that most liver problems that result from niacin are actually due to co-medication.
Anyone taking either Niacin or Nicotinamide should check any medication that they take for conflicts. Personally, I prefer to take Milk Thistle and N-Acetyl Cysteine to keep my liver in the best condition.
I understand that the flush, for some individuals, is intense with only 100 mg but the point that I am making is that the flush with 500 mg is only a bit stronger but it gets enough of the histamines and prostaglandins outof the system that the next round is a little bit less strong. Taking 100 mg 3 times daily just does not completely dispel all of it.
If I take 500 mg in the AM, i get a flush about 50 percent of the time but it often only lasts about 5 to 15 minutes and if I take a second dose at lunch or dinner, no flush.
The first week of full flush niacin, I did get some royal flushes but at 500 mg daily, it has reduced significantly. I do accept that everyone is different.
The one problem that I see with many on these forums is that often people do not stick with things. If they do not get immediate results or they feel some discomfort, they just move on.
In the end, I am not posting this to be argumentative but to insure that everyone has a chance to find the advantages and disadvantages of both forms of B3. Either way, I believe that the RDA for most vitamins is pure bunk.