Also, something that I have been meaning to post to you is some info on xenoestrogens. I think that it's vitally important for you. BTW, as far as antioxidants go, make sure that you get lots of organic produce in your diet...
Good basic info on cleaning up your body/environment here:
http://www.breastcancerchoices.org/strategies.html
and:
Good article. BTW, parabens, a common preservative used in commercial cosmetics, have been found in breast tumors. It's vitally important to avoid this crap. This article focuses on endometriosis but we can apply this to ALL hormonally-influenced cystic growths(FBD, ovarian cysts, etc). http://www.endo101.com/xeno.htm Xenoestrogens Interfere with your Normal Hormones How to avoid Xenoestrogens Critics have proclaimed that these chemicals are for the most part "weak". The body's hormones are at levels of parts per trillion. However, many of the chemicals that affect the hormone systems are routinely found in the serum after sauna at parts per billion. In other words, these chemicals that affect the hormone systems of the human body occur at 100 to 1000 times greater concentration than that of the normal human hormones. One researcher demonstrated that two "weak" estrogens may act synergistically to give a strong estrogen response. Some of these Xenoestrogens like DDE (a metabolite of DDT) may persist in the body fat for decades. Many of these mimicking hormones were previously thought to occur in pesticides. However, many of the newly discovered xenoestrogens are found in every day previously thought to be inert materials. Some of the following is information taken from Our Stolen Future by Theo Colborn: DDT A study published in the Proceedings of the Society of Experimental Biology and Medicine in 1950 by two Syracuse University Zoologists Lindeman and Burlington described how doses of DDT prevented young roosters from developing normally. They injected DDT into roosters by injecting the pesticide into forty young roosters for a period of 2 to 3 months. The daily doses of DDT did not kill the roosters or even made them sick. It made them look weird; they looked like hens. The birds testicles were only 18% of normal size. Their combs and wattles remained stunted and pale. The roosters were chemically castrated. Micheal Fry, a wild life toxicologist, at the University of California at Davis injected eggs from western and California gull colonies with DDT and a breakdown product of DDT, DDE, and methoxychlor (another synthetic pesticide known to bind to estrogen receptors). He found the feminization of the male's reproductive tracts. Typical female cells were found in the testicles, and in cases of higher doses, the presence of an oviduct, the egg-laying canal normally found only in females. Despite all this internal disruption, the chick looked completely normal.
DDT was banned in the United States. However, world wide production of DDT has never been higher. In fact, DDT is manufactured in the United States and shipped to third world countries. DDT is metabolized to DDE in the human body within a few months. DDE then may last in the human body for several decades. However, some medical doctors occasionally find DDT in the serum routinely following intensive sauna. So where is this new exposure to DDT coming from? The United States ships DDT to third world countries that spray it on vegetables and fruits. This agricultural produce is shipped to United States supermarkets where Americans consume it. In 1991, the United States exported 96 tons of DDT. Another source may come from your living area. If your house is near or built upon old agricultural land, DDT will persist in the soil for several centuries. Plastics, Spermicide, Detergent, and Personal Care Products At Tufts Medical School in Boston in 1987, Soto and Sonnenschein serendipitously discovered that plastic test tubes thought to be inert contained a chemical that stimulated breast cancer cells to grow and proliferate wildly. They were experimenting with malignant breast cancer cells that were sensitive to estrogen. When exposed to estrogen the cells would grow and multiply, and when isolated from estrogen, the cells would stop multiplying. During the course of their experiments, they found that the test tube manufacturer changed the formulation of the plastic test tubes that they were using. The manufacturer had used p-nonylphenol one of the family of synthetic chemicals called alkylphenols to make these plastics more stable and less breakable. Manufacturers routinely add nonlyphenols to polystyrene and polyvinyl chloride (PVC). These new plastic test tubes caused their estrogen sensitive breast cancer cells to proliferate, multiply and grow. Thus, they concluded that p-nonylphenol acted like an estrogen.
"These new plastic test tubes caused their estrogen sensitive breast cancer cells to proliferate, multiply and grow" Theo Colborn One study showed that the food processing industry and packaging industry used PVC's that contained nonlyphenols. Another reported contamination of water that had passed through PVC tubing. Even a compound found in contraceptive creams nonoxynol-9 breaks down inside the animal's body to produce nonylphenol. Breakdown of chemicals such as those found in industrial detergents, pesticides, and personal care products give rise to nonylphenol. Global production of alkylphenols polyethoxylate was 600 million pounds in 1990. Although the products purchased by the consumer are not themselves estrogenic; studies have found that bacteria in the animal's bodies, in the environment, or in sewage treatment plants degrade these alkylphenol polyethoxylates, creating nonylphenol and other xenoestrogens. Plastic Drinking Bottles and Plastics used with food In 1993, at Stanford University School of Medicine, Dave Feldman, professor of medicine was experimenting with a yeast estrogen protein that binds to estrogen. They found that the polycarbonate bottles used to hold drinking water contained bisphenol-A. They used the polycarbonate lab flasks to sterilize the water used in their experiments. Bisphenol-A nicely bound to the estrogen protein found in the yeast. This polycarbonate plastic is routinely used for the giant jugs used in shipping water. The manufacturer was aware that the bottles would leach particularly if exposed to high temperatures and caustic cleaners and so developed a washing regimen that they thought would solve the problem. However, the researchers discovered that the manufacturer could not detect samples sent from their lab, samples that were causing proliferation of estrogen responsive breast cancer cells. This proved to be a detection limit in the manufacturer's lab equipment. The Stanford team found that 2-5 parts per billion of bisphenol-A was enough to cause the breast cancer cells to proliferate. Professor Feldman noted that though bisphenol-A is 2000X less potent than estrogen, "it still has activity in the parts per billion range." One Dartmouth University Study showed that plastic wrap heated in a microwave oven with vegetable oil had 500,000 times the minimum amount of xenoestrogens needed to stimulate breast cancer cells to grow in the test tube. John Sumpter a biologist from Brunel University in Uxbridge began to study sexually confused fish reported from anglers fishing in English rivers. Many fish caught in the lagoons and pools just below the discharge from sewage plants looked quite bizarre. Even experienced fisherman could not tell if a fish was male or female. The fish showed male and female characteristics at the same time. They were perfect examples of intersex where an individual is stranded between both sexes. Sumpter used a marker that helped identify female fish. Normally in females a special egg protein is made called vitellogenin, in response to estrogen from the ovaries. On the estrogen signal from the ovaries, the liver produces vitellogenin and the protein is incorporated into the eggs. Since the response is dependent on estrogen, vitellogenin levels found in male fish would be a good indication of estrogen exposure. Caged fish raised in captivity and then kept in the contaminated pools made 1000X to 100,000X more vitellogenin than control trout kept in clean water. 15 sites were sampled with soaring vitellogenin levels. It was a national problem. Alkylphenol levels from detergent breakdown products are high on the suspect list. However, Sumpter suspects that it is the synergistic qualities of several xenoestrogens acting together. Canned Foods Two Spanish Scientists at the University of Granada decided to investigate the plastic coatings that manufacturers use to line the metal cans. The coating is added to avoid the metallic taste of metal in the food from the cans. These linings are present in about 85% of the cans. Fatima Olea and Nicolas Olea, an M.D., specializing in endocrine cancers worked with Soto and Sonnenschein. In a study analyzing twenty brands of canned foods purchased in the United States and in Spain, they discovered bisphenol-A, the same chemical that the Stanford researchers discovered, in about half of the canned food up to levels of 80 parts per billion. This is 27 times greater concentration of bisphenol-A needed to cause the breast cancer cells to proliferate in the Stanford Study. Commercially raised Beef, Chicken and Pork Commercially raised livestock are routinely given xenoestrogens to fatten them up, grow quickly, and cause them to retain water. This results in greater profits for the farmer. It is an effective, cheap, quick way to fatten them up. In the 1970's and 1980's there was an epidemic in Puerto Rico of early puberty in girls as young as a year old and even young boys who developed breasts caused by meat and dairy products containing high levels of estrogen. In the United States, the use of estrogen compounds is now slightly better regulated, but it is still very much used and abused.
DES (diethylstilbestrol), a type of synthetic estrogen, was the first hormone to be used by the meat industry to fatten up livestock until it was discovered that it causes cancer even in extremely minute amounts. Birth Control Pills Birth Control Pills contain a synthetic estrogen and a synthetic progestin to force the body to cycle in a normal manner even though conception may have occurred and different hormones levels are supposed to occur. Is it really nice to fool mother nature? Many times what we see clinically is that it takes one year or more for a woman's period to become normal after stopping birth control pills. This is because the synthetic estrogens and progestins in the birth control pills are oil soluble and difficult for the body to get rid of. Why not use a simpler method of birth control such as condoms? Use one that does not use a spermicide such as nonoxynol-9. Researchers found that once nonoxynol-9 gets into a rats body it breaks down into nonylphenol - a known xenoestrogen. Preservative Methyl Paraben in Skin Lotions and Gels For many years, parabens were considered among those preservatives with low systemic toxicity, primarily causing allergic reactions. However, as we have become aware that some synthetic chemicals mimic the female hormone estrogen, our understanding of the toxic effects of both synthetic and natural substances has changed. Now, John Sumpter from the Department of Biology & Biochemistry, Brunel University, Uxbridge, Middlesex, have found that alkyl hydroxy benzoate preservatives (namely methyl-, ethyl-, propyl-, and butylparaben) are weakly estrogenic. In an estrogen receptor-binding assay, butylparaben was able to compete with the female hormone estradiol for binding to estrogen receptors with an affinity approximately 5 orders of magnitude lower than that of diethylstilbestrol (a highly carcinogenic synthetic estrogen), and between 1 and 2 orders of magnitude less than nonylphenol (an estrogenic synthetic industrial chemical). Although it is reassuring to note that when administered orally, the parabens were inactive, subcutaneous administration of butylparaben produced a positive estrogenic response on uterine tissues. Although approximately 100,000 times less potent than17 beta-estradiol, greater exposure to the parabens may compensate for their lower potency. The researchers conclude that, "Given their use in a wide range of commercially available topical preparations, it is suggested that the safety in use of these chemicals should be reassessed . . ." The European Union has asked the European Cosmetics and Toiletry industry about these new findings and the implication for breast cancer. These preservatives are found in the vast majority of skin an body lotions, even in natural progesterone creams. Generally, for the sterol hormones, taken orally the hormones are 90% first pass metabolized by the liver. Thus, taken orally only 10% reaches the body. In contrast, anything absorbed by the skin is directly absorbed. In other words, anything absorbed through the skin may be as high as 10 times the concentration of an oral dose. Unfortunately, some natural progesterone creams were found to contain methyl and propyl parabens as a preservative. Unfortunately, some natural progesterone creams were found to contain methyl and propyl parabens as a preservative. Shampoos that Purposely Contain Very High Amounts of Estrogen African Americans favored shampoos with clinically active high doses of estrogen. They also used them on their children. In 1998 Tiwary, now retired, published a study of four girls - including a 14-month-old - who developed breasts or pubic hair months after beginning to use such products. The symptoms started to disappear when they stopped using them. The year before, he published a study showing that some of the products used by his patients contained up to one milligram (1 mg) of estradiol per one ounce of shampoo. By comparison a normal adult topical skin dose for estradiol is 0.02-0.05 mg/day. This means that one ounce of shampoo contains 50 times the daily ADULT dose of estradiol. A small handful of this shampoo on your child every day may give her OR HIM breasts!See the article here. Herbicide Tyrone B. Hayes of the University of California at Berkeley found that atrazine, the most commonly used weed killer in North America, affected frogs at doses as small as 0.1 part per billion. As the amount of atrazine increased, as many as 20 percent of frogs exposed during their early development produced multiple sex organs or had both male and female organs. Many had small, feminized larynxes. See the article here. Plastic IV Bags The United States FDA warns that prolonged fluid exposure in IV bags may affect testicle development in young boys. The chemical, called DEHP, can leach from the plastic into certain liquids, especially fat-containing ones like blood. Studies of young animals show the chemical can affect testicle development and production of normal sperm. Some companies already label that their products contain phthalates (DHEP), and the FDA soon will issue a recommendation — not a requirement — that more companies do so. "FDA's public health notification falls far short of what is needed to protect patients," said Charlotte Brody of Health Care Without Harm, a group working to reduce the amount of phthalates — the family of chemicals that includes DEHP — in a variety of products, from plastic toys to cosmetics. 5 Out of 6 Chemicals Used to block UV in Sunscreen are Estrogenic Margaret Schlumpf and her colleagues (Institute of Pharmacology and Toxicology, University of Zurich, Switzerland) have found that many widely-used sunscreen chemicals mimic the effects of estrogen and trigger developmental abnormalities in rats. (Schlumpf , Margaret; Beata Cotton, Marianne Conscience, Vreni Haller, Beate Steinmann, Walter Lichtensteiger. In vitro and in vivo estrogenicity of UV screens. Environmental Health Perspectives Vol. 109 (March 2001) pp 239-244) Her group tested six common chemicals that are used in sunscreens, lipsticks and facial cosmetics. Five of the six tested chemicals (benzophenone-3, homosalate, 4-methyl-benzylidene camphor (4-MBC), octyl-methoxycinnamate and octyl-dimethyl-PABA) behaved like strong estrogen in lab tests and caused cancer cells to grow more rapidly. Only one chemical - a UVA protector called butyl-methoxydibenzoylmethane (B-MDM) - showed no activity. Uterine growth and endometriosis :One very common sunscreen chemical, 4-MBC, was mixed with olive oil and applied to rat skin. This caused a doubling of the rate of uterine growth well before puberty. "That was scary, because we used concentrations that are in the range allowed in sunscreens," said Schlumpf. Three of the six caused developmental abnormalities in animals. The major cause of sterility in women in the USA is endometriosis, a condition afflicting 5.5% of American women. Exposure to excessive estrogen, that may have come from such sunscreens, is felt to be the primary cause of endometriosis. Perhaps a sunscreen using zinc oxide is a better choice. Common Chemical in Personal Care Products, Fragrances, Paints, Plastics and Cosmetics May cause Testicular Defects in Boys For the first time, scientists have shown that pregnant mothers exposed to high but common levels of a widely used ingredient in cosmetics, fragrances, plastics and paints can have baby boys with smaller genitals and incomplete testicular descent. Previous work had shown that prenatal phthalate exposure in rodents can critically affect male hormones, resulting in impaired testicular descent and smaller genital size. The Swan study is the first to look at effects in humans.While none of the boys showed clear malformation or disease, in the 25% of mothers with the highest levels of phthalate exposure, the odds were 10 times higher that their sons would have a shorter than expected distance between the anus and the base of the penis. This so-called AGD measurement is a sensitive indicator of impacts on their reproductive system. See the article here. Summary From a strictly research point of view there may not be enough evidence to create public outrage and shift public opinion. It is a known medical fact that estrogen stimulates breast cancer. However, it is disconcerting to note that the breast cancer rate is now 1 out of 8 women where before breast cancer in the 1950's was 1 out of 20. Dr. Lee believes that overdose of estrogen leads to PMS. The hallmark of PMS is a few pounds of weight gain just before your period. So what do we do? The very important changes to make are do NOT eat food with HOT plastic. Change your laundry detergent, no fabric softener, no dryer sheets, change your lotions, soaps, shampoos, and makeup to avoid parabens. Avoid coffee. Vendors: Living Source (254) 776-4878 for Nature Clean, Green Co. 800-809-0610 for Conti Castile Soap.
Subject: Re: xenoestrogens
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Date: 5/8/2010 8:02:50 PM ( 10 mon ago )
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wombat
Xenoestrogens are found in everyday synthetic materials. These materials were previously thought to be inert. Cut out the xenoestrogens from your life.
by Elizabeth Smith, M.D.
Xeno literally means foreign. So xenoestrogens means foreign estrogens. Some of the 100,000 registered chemicals for use in the world have hormonal effects in addition to toxic and carcinogenic effects. Also the synergistic effects are known to occur but also are largely exactly unknown. The field of xenohormones is new, and only been in existence since about 1991.
DDT was found to bind to the estrogen receptor sites. It is now considered one of the classic xenoestrogens.
"The roosters were chemically castrated by DDT."
Detergent Breakdown Products
"Young boys developed breasts."
John Lee, M.D.
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Shampoos with estrogen? EEEEEEK! I had no idea. I didn't think I could be astonished by manufacturing perfidy anymore :(
Yes! I feel that that info is worth a copy and paste considering that African Americans have the highest mortality rates from cancers...
Ain't nuthin new under the sun, JT! Caveat emptor...we just all have to remember that most commercial products are formulated with profit as the most important consideration.
http://www.endo101.com/shampoo.htm
Shampoos Contain Clinical Doses of Estrogen Unbeknown to many parents, a few hair products - especially some marketed to black people - contain small amounts of hormones that could cause premature sexua| development in girls. The evidence that hair products containing oestrogens cause premature puberty is largely circumstantial, and the case is still unproven. But Ella Toombs, acting director for the Office of Cosmetics and Colors at the US Food and Drug Administration, told New Scientist: "No amount [of oestrogen] is considered safe and can be included in an over-the-counter product." Under FDA regulations, over-the-counter products containing hormones are drugs, and thus require specific approval. However, there appears to be a grey area regarding products marketed before 1994. The FDA failed to respond to a request to clarify the position. At least five companies are still making hormone-containing hair products, a source within the industry - who preferred not to be named - told New Scientist. Throughout the West, girls are tending to reach puberty earlier. This has been blamed on everything from improved diet to environmental contaminants. But African-American girls are developing even earlier than their white counterparts. About half of black girls in the US begin developing breasts or pubic hair by age eight, compared with just 15 per cent of white girls, one study has found. In Africa, girls enter puberty much later, regardless of their socioeconomic status.
That big discrepancy may be explained, at least in part, by the more frequent use of hormone-containing hair products among African Americans, says Chandra Tiwary, former chief of paediatric endocrinology at Brooke Army Medical Center in Texas. "I believe that the frequency of sexua| precocity can be reduced simply if children do not use those hair products," he says. The products are sold as shampoos or treatments to deep-condition dry, brittle hair. The labels usually state that they contain placenta, hormones or "estrogen", although not all products that make such claims contain active hormones. While New Scientist's inquiries suggest such products are no longer sold in Europe, many are still available worldwide over the Internet. And they remain popular among African Americans. A small study published earlier this year by Su-Ting Li of the Child Health Institute in Seattle suggests that nearly half of African-American parents use such products, and that most also use them on their children. For other ethnic groups the figure is under 10 per cent. Tiwary told New Scientist that he has carried out a bigger, as yet unpublished, survey of 2000 households that confirms these findings. In 1998 Tiwary, now retired, published a study of four girls - including a 14-month-old - who developed breasts or pubic hair months after beginning to use such products. The symptoms started to disappear when they stopped using them. The year before, he published a study showing that some of the products used by his patients contained up to four milligrams of oestradiol per 100 grams. Others contained up to two grams of oestriol per 100 grams.
B&B Super Gro, for example, which was marketed before 1994 and is still on sale in the US and claims to be "rich in hormones", was found to contain 1.6 grams of oestriol per 100 grams. While the levels of oestriol in the products were much higher, oestradiol is a far more potent form of oestrogen. There is no doubt that oestrogens are readily absorbed through the skin--hormone therapy is often delivered via patches. Long-term exposure to these doses could cause premature puberty, Tiwary believes. And his studies are not the only ones hinting at a possible effect. Anecdotal reports in scientific papers going back to 1982 describe early puberty in children after use of hair treatments, as well as certain ointments. Tiwary notified the FDA of his concerns in 1994, but says he never received a reply. The evidence that oestrogen-containing hair products cause early puberty remains limited. There are too many other suspect substances to pin the blame on them without further studies. "A person isn't exposed to just one chemical, but rather a mix of many," says Julia Brody, director of the Silent Spring Institute in Massachusetts, a non-profit organisation that looks at the environment and women's health. "There is an increasing awareness that hormonally active compounds are present in cosmetic products." Hormone-Containing Hair Product Use in Prepubertal ChildrenSome cosmetics contain estrogens, representing a potential source of exogenous estrogen for children. In contrast to pharmaceutical preparations, the Food and Drug Administration (Rockville, Md) does not regulate cosmetics containing less than 10 000 IU of estrogen per ounce, only stating that the label should direct consumers to limit the amount of product used to less than 20 000 IU/mo.1, 2 A therapeutic dose of oral ethinyl estradiol for hormone-replacement therapy in adults is 0.02 to 0.05 mg/d (4000-10 000 IU/d). An equivalent therapeutic transdermal estradiol dose for hormone-replacement therapy is 0.05 mg/d. Two case series suggest that exogenous hormones found in hair products may be associated with early pubertal development in African American girls.2, 3 In 3 of 4 cases, pubertal characteristics regressed on discontinuation of these products.3 Patterns of use of hormone-containing hair products (HCHPs) are unknown. One survey of parents at 4 southern US Army hospital clinics revealed that 64% of African American parents and 6.9% of European-American parents used HCHPs, and 55.5% of those parents used them on their children.4 We estimated the prevalence of HCHP use among different ethnic groups in an urban clinic population, which included immigrant populations. We surveyed parents with children younger than 10 years attending 3 Seattle, Wash, pediatric clinics between November 1999 and January 2000. Color copies of product labels of HCHPs were used as pictorial guides. Age, sex, and frequency of exposure to HCHPs were documented to better understand whether prepubertal children were regularly exposed to these products. A total of 130 parents were surveyed. Race/ethnicity was reported as follows: 25% African American, 25% African immigrant, 20% European American, 12% Asian/Pacific Islander, 11% Hispanic, and 6% other/unspecified. Of the 247 children reported, 55% were girls, 41% were boys, and 4% did not specify sex. Age group distribution was as follows: 8%, younger than 1 year; 48%, 1 to 5 years; 26%, 6 to 9 years; and 19%, 10 to 18 years. The use of HCHPs was reported by 21% (27/130) of respondents (Table 1). More African American parents (45%) used HCHP than parents of all other races/ethnicities (2 = 16.4; P<.001), including African immigrant parents (12%). Eighty-five percent of parents using HCHPs also used these products on their children, including children younger than 5 years. Most families (65%) who used HCHPs on their children used them only occasionally but a third of families reported regular use. One limitation of this study is that we were unable to quantitate the exact dose or absorption of these products. A recent study revealed that girls are developing at an earlier age than has been observed previously and there is a significant difference between mean age of onset of puberty in European American compared with African American girls.5, 6 Since it is unknown why African American girls are entering puberty at an earlier age than their European American or African counterparts, it is possible that the use of HCHPs may contribute to earlier onset of puberty in this population. More research is needed to ascertain whether an association exists between the use of HCHPs and the early onset of puberty. Relevancy 0.82Pediatrics & Adolescent Medicine / volume:156 (page: 85) Hormone-Containing Hair Product Use in Prepubertal Children Su-Ting T. Li, MD; Paula Lozano, MD, MPH; David C. Grossman, MD, MPH; Elinor Graham, MD, MPH January 2002 ABSTRACT | FULL TEXT | PDF (75K) Su-Ting T. Li, MD Child Health Institute 146 N Canal St, Suite 300 Seattle, WA 98103-8552 (e-mail: sli@u.washington.edu) Paula Lozano, MD, MPH David C. Grossman, MD, MPH Elinor Graham, MD, MPH Seattle 1. Estrogens in cosmetics. Med Lett Drugs Ther. 1985;27:54-55. MEDLINE 2. Zimmerman PA, Francis GL. Hormone-containing cosmetics may cause signs of early sexua| development. Mil Med. 1995;160:628-630. MEDLINE 3. Tiwary CM. Premature sexua| development in children following the use of estrogen- or placenta-containing hair products. Clin Pediatr. 1998;37:733-739. 4. Tiwary CM. A survey of use of hormone/placenta-containing hair preparations by parents and/or children attending pediatric clinics. Mil Med.1997;162:252-256. MEDLINE 5. Herman-Giddens ME, Slora EJ, et al. Secondary sexua| characteristics and menses in young girls seen in office practice: a study from the Pediatric Research Office Settings Network. Pediatrics. 1997;99:505-512. MEDLINE 6. Kaplowitz PB, Oberfield SE. Reexamination of the age limit for defining when puberty is precocious in girls in the United States: implications for evaluation and treatment. Pediatrics. 1999;104:936-941. MEDLINE |