Hi, My pyrrole reading was normalised at 100, I undermythylate, and have high histamine. I am 44 and also thought it was part of who I was (due to my screwed up childhood) and also because I too abuse Sugar and Know that it effects my moods.
I had No tolerance to stress, moody, lots on the list, but good energy. I have been on SAMe for months/year(s) as I found it kept me boyant and motivated so I didn't fall into depression/apathy. Turns out I need that for the methylation.
My mother has been telling me to take B6 for eons - you must have known something to start taking it prior to your testing, and I would think it would effect your tests, but not sure.
If you have a mindset that is suspicious of people (think that they take advantage of you) then I can understand you being dubious about Pfeiffer - I'm in Australia but the doc I found is affiliated. I think it is great there are a growing body of doctors that recognise nutrition effects mood/chemistry & psych health. In my experience on the supplements to date (about 3 weeks) it does. I feel more normal, 'nicer' I have more patience, tolerance to stress and less racey thoughts. It has helped my relationship as I am not so reactive or moody.
But its not to say I don't still snap at my kids when they act up or get annoyed when they touch or poke me when I am eating (why they have to do that I'll never know!).

I had massive abandonment issues also - I worked on a lot during years of therapy and it helped, but I still had enduring 'traits' I wished weren't there and no amount of personal work or awareness seemed to help. Amongst these were many of the things on the list of pyrrole disorder (and many not - like not being able to tan!!??) easy to anger, bit ADD, anxious, easily overwhelmed etc. So I am very happy to have had my 'edge' taken off by the supplements. It made me see the difference between what I could work through with a good therapist and ongoing personal responsibility, and what was being caused by imbalanced brain chemistry.
I have also studied psychology for years, and I am fascinated by new research into the changes in the brain produced by therapy and also how brain chemistry and past trauma effects behaviour and relationships.
You could be an enneatype four and if you care to read up on this it might help some insight into how your personality has developed around your abandonment etc.
I am interested to hear your story as it begins to answer my questions about how much psychological issues can be treated by vitamins and fixing up brain chemistry etc. While you might need to be on supplements for longer, my doc told me I should see results within four weeks, and I have.
It makes sense to me that I am not so jumpy because my 'nerves' have what they need. LIkewise, when my brain has the neurotransmitter material, esp stuff for serotonin and GABA, I am likely to feel less depressed and calmer. I am yet to uncover the neural/chemical relationship to hoarding - which I realised I had been doing to a small degree since being on supplements.

However, I don't think unprocessed trauma regarding bonding relationships is not going to be eliminated by more of the right neurotransmitters... or exorcism for that matter.
Your symptoms would present a picture of someone who has been pretty badly treated by someone who was meant to look after you when you were little - this isn't to say you were and I apologise if I am wrong. If I am not You could have a look at self psychology theory of Kohut.
Treating the pyroluria will help your anxiety (hypervigilence, social) but won't undo the deficit in 'basic trust' of other humans (Karen Horney). Finding a good therapist you can trust will help this - someone who has done their own work and works with 'object relations' or 'attachment theory'.
Hope this helps and its not too heady:-) In short, good luck, the supplements are helping you, suffice to say that one pill (or 6 like I am taking) will not fix all. Hang in there:-)

Hi there, it sounds like you've been through a similar journey to me....the hypervigilance, the rage, abandonment issues, panic attacks and on and on.

I've just recently posted an article about my personal journey with Pyroluria and also other health problems you can read about here if you like ~ http://hubpages.com/hub/Pyroluria-and-Parasitesa-Journey-back-to-health


It doesn't go too in depth into all that I suffered with, but it gives an idea of how bad things got for me. Also what helped me. I've also written an article on Pyroluria. I'm a qualified naturopath, I also have pyroluria and I'm in recovery with some pretty substantial improvements. It wasn't all nutrients though. I had to change my diet, address my digestive issues (which were severe). I still spiral into now only mild schizophrenic episododes and panic if I overdo it, or over indulge in sweets for too long. I'm still learning about balance and most importantly self love and nurturing, and my children are still really young, so there is never a guarentee that I'm going to get any sleep. Things are getting better though.

Hopefully my articles may provide you with some alternative insight into what might better help you fully recover. Here's the link - http://hubpages.com/hub/Pyroluria-Do-you-have-it


Wishing you well