This is a bit technical ......
The term lecithin itself has different meanings when used in chemistry and biochemistry than when used commercially.
Chemically, lecithin is phosphatidylcholine.
Commercially, it refers to a natural mixture of neutral and polar lipids. Phosphatidylcholine, which is a polar lipid, is present in commercial lecithin in concentrations of 20 to 90%. Most of the commercial lecithin products contain about 20% phosphatidylcholine.
Lecithins containing phosphatidylcholine are produced from vegetable, animal and microbial sources, but mainly from vegetable sources. Soybean, sunflower and rapeseed are the major plant sources of commercial lecithin. Soybean is the most common source. Plant lecithins are regarded as safe. Egg yolk lecithin is not a major source of lecithin in nutritional supplements. Eggs themselves naturally contain from 68 to 72% phosphatidylcholine, while soya contains from 20 to 22% phosphatidylcholine.
The fatty acid makeups of phosphatidylcholine from plant and animal sources are different. Saturated fatty acids, such as palmitic and stearic, make up 19 to 24% of soya lecithin; the monounsaturated oleic acid contributes 9 to 11%; linoleic acid provides 56 to 60%; and alpha-linolenic acid makes up 6 to 9%. In egg yolk lecithin, the saturated fatty acids, palmitic and stearic, make up 41 to 46% of egg lecithin, oleic acid 35 to 38%, linoleic acid 15 to 18% and alpha-linolenic 0 to 1%. Soya lecithin is clearly richer in polyunsaturated fatty acids than egg lecithin.
Choline comprises about 15% of the weight of phosphatidylcholine.
Phosphatidylcholine is absorbed into the mucosal cells of the small intestine, mainly in the duodenum and upper jejunum, following some digestion by the pancreatic enzyme phospholipase. This forms Phosphatidylcholine which is transported in the blood in various lipoprotein particles. It is then distributed to the various tissues of the body. Some phosphatidylcholine is incorporated into cell membranes.
Phosphatidylcholine is also metabolized to choline, fatty acids and glycerol. Blood choline levels peak between 2 to 6 hours after eating.
Phosphatidylcholine may be indicated to help restore liver function in a number of disorders, including alcoholic fibrosis, and possibly viral hepatitis.
Clinical studies have demonstrated that choline is essential for normal liver function. Phosphatidylcholine is a better form and is also more tolerable than choline. But, in addition, research has shown that phosphatidylcholine, independent of its choline content, has striking hepatoprotective effects.
In addition, phosphatidylcholine has demonstrated other protective effects in non-alcoholic liver disorders, including protection against various other toxic substances. Its benefits in viral hepatitis were reported some years ago by several different research groups in Europe and elsewhere. In one of these studies, individuals suffering from hepatitis type A and B were given 1.8 grams of phosphatidylcholine daily. Compared with unsupplemented controls, the phosphatidylcholine group enjoyed quicker recoveries, fewer relapses and quicker normalization of liver function tests.
Researchers in Great Britain treated chronic active hepatitis C patients with 3 grams daily of phosphatidylcholine in double-blind fashion. The phosphatidylcholine patients had significantly reduced symptoms, compared with controls. All evidence of the disease disappeared in some cases. These researchers think that phosphatidylcholine's possible antiviral effects are related to the supplement's apparent ability to increase cellular membrane fluidity and repair the membranes of liver cells.