it is a matter of preference. When I was oil pulling, I used it in each pull. When I stopped oil pulling (due to not enough time in the morning...waiting for the energy to kick in), I continued with the oregano oil. When I stopped taking it, I got a head cold. I took it every day for 3 months, give or take a week.
There are some on here that say no. I say do what feels best for you, until it no longer feels best.