Because the host response to A. lumbricoides in humans is mild, neuroimaging might be expected to provide a number of clues to suggest this organism as the cause of an intracranial lesion. In Case 1, the lesion was not visible in a high-quality noncontrast CT scan, even in retrospect. The amount of tissue reaction was small, as was the region of central enhancement. In addition, cerebral ascariasis may deliver enteric bacteria to the central nervous system, causing the more extensive findings typical of an abscess, as demonstrated in Case 2.