Re: ala without dmsa

"A serious concern with alpha-lipoic acid is that it can facilitate
the movement of mercury out of and into the cells. It can be very
useful in mobilizing mercury from within the cells and making it
available for DMSA to chelate. Without the DMSA to "grab" the mercury
from lipoic acid, it may readily enter other tissues."


Whoever wrote this doesn't understand the concept of dosing drugs at the half life. When ALA is dosed at the half life the conc of DHLA (the active component that chelates) is relatively constant and it is the DHLA that will grab mercury when another DHLA drops it.

Dosing drugs at the half life is a very well known concept in pharmacology. It is surprising that Andy seems to be the only expert in the chelation field who gets it. Tweet