I made some milk thistle seed tincture a few months ago. Had some success with it, but nothing spectacular. I was taking the largest dose that I had heard of, 40 drops. A few days ago I decided to measure 40 drops and found it to be only a fraction of a teaspoon. So, I upped the dose to a full teaspoon. Wow, what a difference! I immediately felt more aware and more energetic. I upped the dose to a teaspoon twice a day, and would take more if it weren't for the 50% alcohol in the tincture. MH, what herbs compliment milk thistle to rebuild the liver?