I wake up at 4am to 5am with reflux everyday for 10 years now. I have tried all the brand name prescriptions and hurt myself more.
I have just started to take aloe vera gel, it helps me for hours. I know that all prescription drugs have side effects. The acid blockers weakens your sphincter and can give you a hiatal hernia. The other thing has helped me is vegetable enzymes. You may want to try those.