I don't think O2 as a component is necessary as an ingredient to help ppl, that is, helps the O2 to work in them - - - I know COQ10 does help ppl in that it does something with an enzyme that does this and that and somehow helps ppl. Ppl (even dr's) call COQ10 an oxygen pill but it has no oxygen in it. I wonder if this is a little like COQ10 in that McCabe claims, "they create natural enzyme/chlorite combinaions that supply the immune and energy production enzymes with some basic chemicals they need to function".